SPICE
RIASSUNTO
La prevalenza del diabete è in costante aumento in tutto il mondo e si stima che raggiungerà oltre 300 milioni di casi entro il 2030. Nonostante i significativi progressi compiuti con l’uso di agenti antidiabetici orali, i trattamenti attuali sono lungi dall’essere perfetti e la ricerca di nuove alternative è più importante che mai. L’obiettivo principale di SPICE è la valorizzazione del potenziale nutraceutico-antidiabetico dei frutti di sommacco (Rhus coriaria), un grande arbusto eretto che cresce in Sicilia allo stato selvatico principalmente su terreni marginali e coltivato in Medio Oriente per la produzione di una spezia anch’essa denominata sommacco, ottenuta dalle drupe essiccate. Una caratterizzazione fitochimica dettagliata sarà associata a specifici meccanismi biologici coinvolti nella modulazione della regolazione glicemica, per identificare classi specifiche di composti fenolici responsabili di tali attività, cercando anche di chiarirne gli effetti sinergici.
Codice Identificativo: Prin 2022 PNRR, CUP: J53D23014470001
Costo totale del progetto: 204.852 euro
Costo totale DAFNE: 47.500,44 euro
Ruolo DAFNE: Responsabile Unità Operativa
Responsabile Scientifico DAFNE: Prof. Luca Santi
Email: luca.santi@unitus.it
Data inizio: 30/11/2023
Data fine: 30/11/2025
LINK
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PARTNERNARIATO
Università degli Studi di Messina; Università Campus Bio-Medico di Roma
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